Largest employers
This table lists Jefferson County’s largest non-governmental employers.
| Company | Employees | Classification |
|---|---|---|
| Continental Tire | 3496 | Manufacturing |
| SSM Health Good Samaritan Hospital Center | 2138 | Healthcare |
| Walgreens Distribution Center | 1484 | Regional Distribution |
| Walmart | 380 | Retail |
| National Railway Equipment Company | 376 | Manufacturing |
| Crossroads Community Hospital | 290 | Healthcare |
| Spero | 197 | Service |
| Kroger | 130 | Retail |
| Peoples National Bank | 102 | Banking |
| NAPA Distribution Center | 90 | Distribution |
| Durham Bus Service | 84 | Transportation |
| Orthopedic Center of Southern Illinois | 78 | Medical Billing |
| Medline | 77 | Healthcare |
| Magnum Steelworks | 50 | Manufacturing |
| Mt. Vernon Neon Sign | 38 | Manufacturing |
| Innotech | 35 | Manufacturing |